Cap-analysis gene expression (CAGE) (Record no. 12017)

MARC details
000 -LEADER
fixed length control field 03957nam a2200349Ia 4500
001 - CONTROL NUMBER
control field PSP0NE10566PDF
003 - CONTROL NUMBER IDENTIFIER
control field BD-DhSAU
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20151012144309.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS
fixed length control field m|||||o||d||||||||
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr||||
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 120329s2010 si a sb 001 0 eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9789814241359 (ebook : PDF)
040 ## - CATALOGING SOURCE
Original cataloging agency BD-DhSAU
Transcribing agency BD-DhSAU
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (OCLC)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) QH450
Local cutter number (OCLC) ; Book number/undivided call number, CALL (RLIN) .C37 2010
092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC)
Classification number 572.86
Item number C236
245 00 - TITLE STATEMENT
Title Cap-analysis gene expression (CAGE)
Medium [electronic resource] :
Remainder of title the science of decoding gene transcription /
Statement of responsibility, etc. editor, Piero Carninci.
246 3# - VARYING FORM OF TITLE
Title proper/short title Cap analysis gene expression (CAGE)
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. Singapore :
Name of publisher, distributor, etc. Pan Stanford,
Date of publication, distribution, etc. c2010.
300 ## - PHYSICAL DESCRIPTION
Extent xv, 266 p. :
Other physical details ill. (some col.).
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes bibliographical references and indexes.
505 2# - FORMATTED CONTENTS NOTE
Formatted contents note Cap analysis gene expression (CAGE) -- Tagging transcription starting sites with CAGE -- Construction of CAGE libraries -- Transcriptome and genome characterization using massively parallel paired end tag (PET) sequencing analysis -- New era of genome-wide gene expression analysis -- Computational tools to analyze CAGE -- Extraction and quality control of CAGE tags -- Setting CAGE tags in a genomic context -- Using CAGE data for quantitative expression -- Databases for CAGE visualization and analysis -- Computational methods to identify transcription factor binding sites using CAGE information -- Transcription regulatory networks analysis using CAGE -- Gene-expression ontologies and tag-based expression profiling -- Lessons learned from genomic CAGE -- Future challenges in CAGE analysis -- Comparative genomics and mammalian promoter evolution -- The impact of CAGE data on understanding macrophage transcriptional biology.
520 1# - SUMMARY, ETC.
Summary, etc. "The ouput of eukaryotic genomes is much more complex than expected. Genes produce different variants of RNAs from multiple promoters. One of the ultimate targets of biological analysis is to establish a relationship between the messenger RNAs that are transcribed from the genome and the genomic regions that control their expression - the promoters - in order to decipher the networks that regulate gene expression and the transcription factors that act as master regulators of transcriptional control."
520 8# - SUMMARY, ETC.
Summary, etc. "Novel technologies have recently appeared that allow deciphering of transcriptional network, based on the identification of the starting site of gene transcription, with the simultaneous measurement of expression level and identification of the promoter elements. These tagging technologies (including cap-analysis gene expression - CAGE - and others) are further boosted from the development of the novel generation of sequencing instruments, which allow transcriptional profiling by sequencing at the cost of microarray experiments."
520 8# - SUMMARY, ETC.
Summary, etc. "This book is a guide for users of new technologies, as it includes accurately proven protocols, allowing readers to prepare their samples for experiments. Additionally, it provides a guide for the bioinformatics tools that are available for the analysis of the obtained tags, including the design of the software, the sources and web information where they can be downloaded. Finally, the book provides examples of the application of these technologies to identify promoters, annotate genomes, identify new RNAs and reconstruct models of transcriptional control. Although examples mainly regard mammalians, the discussion expands to other groups of eukaryotes, where these approaches are complementing genome sequencing"--P. [4] of cover.
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Also available in print edition.
538 ## - SYSTEM DETAILS NOTE
System details note Mode of access: World Wide Web.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Gene expression.
655 #7 - INDEX TERM--GENRE/FORM
Genre/form data or focus term Electronic books.
Source of term lcsh
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Carninci, Piero.
776 1# - ADDITIONAL PHYSICAL FORM ENTRY
International Standard Book Number 9789814241342 (hardback)
-- 9814241342 (hardback)
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://marc.crcnetbase.com/isbn/9789814241359">http://marc.crcnetbase.com/isbn/9789814241359</a>
Electronic format type application/PDF

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