Randomized response-adaptive designs in clinical trials / Anthony C. Atkinson, Emeritus Professor of Statistics, London School of Economics, UK, Atanu Biswas, Professor, Indian Statistical Institute, Kolkata, India.

By: Atkinson, A. C. (Anthony Curtis) [author.]Contributor(s): Biswas, Atanu, 1970- [author.]Material type: Text

TextSeries: Monographs on statistics and applied probability (Series) ; 130.Publisher: Boca Raton : CRC Press/Taylor & Francis Group, [2014]Copyright date: �2014Description: 1 online resource : text file, PDFContent type: text Media type: computer Carrier type: online resourceISBN: 9781584886945 (ebook : PDF)Subject(s): Clinical trialsGenre/Form: Electronic books.Additional physical formats: Print version:: No titleOnline resources: Click here to access online Also available in print format.

Contents:

0. Introduction : stories and data -- 1. Adaptive design : controversies and progress -- 2. Randomized balanced sequential treatment allocation -- 3. Response-adaptive designs for binary responses -- 4. Response-adaptive designs for continuous responses -- 5. Response-adaptive designs for longitudinal responses -- 6. Optimum biased-coin designs with covariates -- 7. Optimum response-adaptive designs with covariates -- 8. Optimal response-adaptive designs with constraints -- 9. Adaptive design : further important issues.

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