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Beyond apoptosis [electronic resource] : cellular outcomes of cancer therapy / edited by Igor B. Roninson, J. Martin Brown, Dale E. Bredesen.

Contributor(s): Roninson, Igor B | Brown, J. M. (J. Martin) | Bredesen, Dale EMaterial type: TextTextPublication details: New York : Informa Healthcare, c2008. Description: xi, 352 p. : illISBN: 9781420020502 (ebook : PDF)Subject(s): Cancer -- Chemotherapy | ApoptosisGenre/Form: Electronic books.Additional physical formats: No titleOnline resources: Click here to access online Also available in print edition.
Contents:
1. A personal history of the development of the apoptosis concept / John F.R. Kerr -- 2. What do the clinical data tell us about the role of apoptosis in sensitivity to cancer therapy? / George D. Wilson -- 3. Response of solid tumors to cancer therapy : how relevant is apoptosis? / J. Martin Brown -- 4. Historical studies of various forms of programmed cell death / Richard A. Lockshin and Zahra Zakeri -- 5. Toward a mechanistic taxonomy for programmed cell death pathways / Dale E. Bredesen -- 6. Caspase-independent apoptotic cell death / Lotti Egger -- 7. Autophagic cell death in mammalian cells / David T. Madden -- 8. The cellular decision between apoptosis and autophagy / Yongjun Fan, Erica Ullman, and Wei-Xing Zong -- 9. Parthanatos : PARP and AIF-dependant programmed cell death / Valina L. Dawson and Ted M. Dawson -- 10. Paraptosis / Sabina Sperandio and Ian de Belle -- 11. Cellular senescence and its effects on carcinogenesis / Judith Campisi -- 12. Tumor-suppressing activities of senescent keratinocytes / Brian J. Nickoloff -- 13. Senescence induced by repression of human papillomavirus oncogenes in cervical cancer cells / Daniel DiMaio ... [et al.] -- 14. Treatment-induced tumor cell senescence and its consequences / Igor B. Roninson and Eugenia V. Broude -- 15. Senescence regulation in cancer therapy / Abdelhadi Rebbaa -- 16. Exploiting drug-induced senescence in transgenic mouse models / Mehtap Kilic and Clemens A. Schmitt -- 17. Therapy-induced cellular senescence : clinical relevance, implications, and applications / Daniel Y. Wu ... [et al.] -- 18. Mitotic catastrophe in cancer therapy / Eugenia V. Broude ... [et al.] -- 19. How do cells die after irradiation? Time-lapse studies of cells in culture / William C. Dewey -- 20. Modes of cell death by anticancer agents : the crucial importance of dose / J. Martin Brown.
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Includes bibliographical references and index.

1. A personal history of the development of the apoptosis concept / John F.R. Kerr -- 2. What do the clinical data tell us about the role of apoptosis in sensitivity to cancer therapy? / George D. Wilson -- 3. Response of solid tumors to cancer therapy : how relevant is apoptosis? / J. Martin Brown -- 4. Historical studies of various forms of programmed cell death / Richard A. Lockshin and Zahra Zakeri -- 5. Toward a mechanistic taxonomy for programmed cell death pathways / Dale E. Bredesen -- 6. Caspase-independent apoptotic cell death / Lotti Egger -- 7. Autophagic cell death in mammalian cells / David T. Madden -- 8. The cellular decision between apoptosis and autophagy / Yongjun Fan, Erica Ullman, and Wei-Xing Zong -- 9. Parthanatos : PARP and AIF-dependant programmed cell death / Valina L. Dawson and Ted M. Dawson -- 10. Paraptosis / Sabina Sperandio and Ian de Belle -- 11. Cellular senescence and its effects on carcinogenesis / Judith Campisi -- 12. Tumor-suppressing activities of senescent keratinocytes / Brian J. Nickoloff -- 13. Senescence induced by repression of human papillomavirus oncogenes in cervical cancer cells / Daniel DiMaio ... [et al.] -- 14. Treatment-induced tumor cell senescence and its consequences / Igor B. Roninson and Eugenia V. Broude -- 15. Senescence regulation in cancer therapy / Abdelhadi Rebbaa -- 16. Exploiting drug-induced senescence in transgenic mouse models / Mehtap Kilic and Clemens A. Schmitt -- 17. Therapy-induced cellular senescence : clinical relevance, implications, and applications / Daniel Y. Wu ... [et al.] -- 18. Mitotic catastrophe in cancer therapy / Eugenia V. Broude ... [et al.] -- 19. How do cells die after irradiation? Time-lapse studies of cells in culture / William C. Dewey -- 20. Modes of cell death by anticancer agents : the crucial importance of dose / J. Martin Brown.

Also available in print edition.

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