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Scalable green chemistry : case studies from the pharmaceutical industry / edited by Stefan G. Koenig.

Contributor(s): Material type: TextPublisher: Boca Raton, Fla. : CRC Press : Pan Stanford Publishing, [2013]Description: 1 online resource : text file, PDFContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9789814364812 (ebook : PDF)
Subject(s): Genre/Form: Additional physical formats: Print version:: No titleOnline resources: Available additional physical forms:
  • Also available in print format.
Contents:
1. Introduction to green pharmaceutical science : fact, fiction, and future / Julie B. Manley -- 2. Green chemistry in drug development / Apurba Bhattacharya, Siddhartha Akasapu, and Rakeshwar Bandichhor -- 3. Development of green-by-design, practical biocatalytic processes / Gjalt W. Huisman and Steven J. Collier -- 4. Application of green metrics to scalable industrial synthesis plans : approaches to Oseltamivir Phosphate (Tamiflu�) / John Andraos -- 5. The road to becoming green : process development of AR-A2, an active pharmaceutical ingredient with antidepressant activity / Hans-J�urgen Federsel, Martin Hedberg, Fredrik R. Qvarnstr�om, and Wei Tian -- 6. Improved and greener process for pioglitazone and its pharmaceutically acceptable salts / Apurba Bhattacharya, Rakeshwar Bandichhor, and Lokeswara Rao Madivada -- 7. The development of a convergent green synthesis of linezolid, an oxazolidinone antibacterial agent / William R. Perrault, James B. Keeler, William C. Snyder, Christian L. Clark, Michael R. Reeder, Richard J. Imbordino, Rebecca M. Anderson, Nabil Ghazal, Stephen L. Secreast, and Bruce A. Pearlman -- 8. Development of a nonaqueous process for the synthesis of 3-Amino-pentan-1, 5-diol / Thimma Rawalpally and Thomas Cleary -- 9. Development of a robust, environmentally responsible process for the manufacture of Tofacitinib Citrate / Rajappa Vaidyanathan -- 10. Selective nitration under cGMP conditions / Peter Poechlauer, Sascha Braune, and Roland Oberm�uller -- 11. Going green using combined real-time analytics and process automation / Dominique Hebrault and Terry Redman -- 12. Approaches to the scale-up of organic chemistry using microwave heating / Nicholas E. Leadbeater -- 13. Challenges faced and future directions / Stefan G. Koenig.
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Includes bibliographical references and index.

1. Introduction to green pharmaceutical science : fact, fiction, and future / Julie B. Manley -- 2. Green chemistry in drug development / Apurba Bhattacharya, Siddhartha Akasapu, and Rakeshwar Bandichhor -- 3. Development of green-by-design, practical biocatalytic processes / Gjalt W. Huisman and Steven J. Collier -- 4. Application of green metrics to scalable industrial synthesis plans : approaches to Oseltamivir Phosphate (Tamiflu�) / John Andraos -- 5. The road to becoming green : process development of AR-A2, an active pharmaceutical ingredient with antidepressant activity / Hans-J�urgen Federsel, Martin Hedberg, Fredrik R. Qvarnstr�om, and Wei Tian -- 6. Improved and greener process for pioglitazone and its pharmaceutically acceptable salts / Apurba Bhattacharya, Rakeshwar Bandichhor, and Lokeswara Rao Madivada -- 7. The development of a convergent green synthesis of linezolid, an oxazolidinone antibacterial agent / William R. Perrault, James B. Keeler, William C. Snyder, Christian L. Clark, Michael R. Reeder, Richard J. Imbordino, Rebecca M. Anderson, Nabil Ghazal, Stephen L. Secreast, and Bruce A. Pearlman -- 8. Development of a nonaqueous process for the synthesis of 3-Amino-pentan-1, 5-diol / Thimma Rawalpally and Thomas Cleary -- 9. Development of a robust, environmentally responsible process for the manufacture of Tofacitinib Citrate / Rajappa Vaidyanathan -- 10. Selective nitration under cGMP conditions / Peter Poechlauer, Sascha Braune, and Roland Oberm�uller -- 11. Going green using combined real-time analytics and process automation / Dominique Hebrault and Terry Redman -- 12. Approaches to the scale-up of organic chemistry using microwave heating / Nicholas E. Leadbeater -- 13. Challenges faced and future directions / Stefan G. Koenig.

Also available in print format.

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