Thyroid cancer [electronic resource] : from emergent biotechnologies to clinical practice guidelines / edited by Angelo Carpi, Jeffrey I. Mechanick.

Contributor(s): Carpi, A. (Angelo) | Mechanick, Jeffrey IMaterial type: Text

TextPublication details: Boca Raton : CRC Press, 2011. Description: xvii, 390 p., [8] p. of plates : ill. (some col.)ISBN: 9781439862223 (ebook : PDF)Subject(s): Thyroid gland -- Cancer | Thyroid gland -- Cancer -- DiagnosisGenre/Form: Electronic books.Additional physical formats: No titleOnline resources: Click here to access online Also available in print edition.

Contents:

ch. 1. Principles of translational medicine and applications to thyroid cancer investigation / Emily Jane Gallagher and Derek LeRoith -- ch. 2. Systems biology : an overview / Ravi Iyengar and Azi Lipshtat -- ch. 3. Genetic and epigenetic alterations in the MAP kinase and PI3K/Akt pathways in thyroid cancer / Mingzhao Xing and Paul W. Ladensen -- ch. 4. Genetic and molecular pathophysiology of medullary thyroid carcinoma / Rosa Maria Paragliola ... [et al.] -- 5. Risk stratification in differentiated thyroid cancer / Giuseppe Barbesino -- 6. Clinical practice guidelines for thyroid cancer : where are we now? / Jeffrey I. Mechanick -- 7. Illustrative case studies of thyroid carcinoma and the emerging role of molecular medicine / Donald A. Bergman and Rhoda H. Cobin -- ch. 8. Advances in thyroid ultrasound for detection and follow-up of thyroid malignancies : technical and clinical aspects / Laurence Leenhardt, Fran�cois Tranquart, and Jean Tramalloni -- ch. 9. Multimodality imaging and aspiration biopsy guidance in the perioperative management of thyroid carcinoma / Jing Gao, Jonathan K. Kazam, and Elias Kazam -- ch. 10. The use of diagnostic radiotracers in thyroid cancer / Josef Machac -- ch. 11. PET-CT scanning in the management of thyroid cancer : experience with a cohort of 100 patients / Dario Casara ... [et al.] -- ch. 12. The emerging role of percutaneous needle biopsy and molecular tumor marker analysis for the preoperative selection of thyroid nodules / Angelo Carpi, Jeffrey I. Mechanick, and Andrea Nicolini -- ch. 13. Image-guided mini-invasive ablation of thyroid tumors and distant metastases / Enrico Papini ... [et al.] -- ch. 14. Thyroidectomy and neck exploration : new surgical approaches / Jean-Christophe Lifante and William B. Inabnet III -- ch. 15. Thyroid surgery performed under local anesthesia and same-day surgery / Joseph DiNorcia and John D. Allendorf -- ch. 16. The use of therapeutic radiotracers in thyroid cancer / Josef Machac -- ch. 17. External beam radiation therapy in thyroid cancer / Walter Choi and Louis Harrison -- ch. 18. Role of chemotherapy in thyroid cancer / Paolo Bossi and Laura D. Locati -- 19. Role of NF-kB in thyroid cancer / Eriko Suzuki, Shunichi Yamashita, and Kazuo Umezawa -- ch. 20. Biologically targeted therapies for thyroid cancers / Steven I. Sherman -- ch. 21. Molecular targeted therapies of medullary thyroid carcinoma / Francesco Torino ... [et al.] -- ch. 22. Synthesis of emergent biotechnologies into future CPG / Jeffrey I. Mechanick ... [et al.].

Summary: "Thyroid cancer evaluation and treatment has enjoyed very little evolution in comparison with other disease management strategies. The standard treatment algorithms for thyroid cancer have varied only in response to major, though infrequent, biotechnological innovations. These resultant algorithm node insertions produced paradigm changes, but there has been little to advance the care of the patient with advanced thyroid cancer--until very recently. Perhaps the reasons for a relative lack of interest and scientific progress are the overwhelming likelihood of benignity among thyroid nodules, the overwhelmingly favorable clinical outcome even if a patient has thyroid cancer, and the overwhelming long time required for clinical follow-up of these cancer patients. Unfortunately, the problem now is that we may be overmanaging low-risk patients, and we have not achieved the clinical responses we would have liked with high-risk patients"--Provided by publisher.

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Includes bibliographical references and index.

"Thyroid cancer evaluation and treatment has enjoyed very little evolution in comparison with other disease management strategies. The standard treatment algorithms for thyroid cancer have varied only in response to major, though infrequent, biotechnological innovations. These resultant algorithm node insertions produced paradigm changes, but there has been little to advance the care of the patient with advanced thyroid cancer--until very recently. Perhaps the reasons for a relative lack of interest and scientific progress are the overwhelming likelihood of benignity among thyroid nodules, the overwhelmingly favorable clinical outcome even if a patient has thyroid cancer, and the overwhelming long time required for clinical follow-up of these cancer patients. Unfortunately, the problem now is that we may be overmanaging low-risk patients, and we have not achieved the clinical responses we would have liked with high-risk patients"--Provided by publisher.

Also available in print edition.

Mode of access: World Wide Web.

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