000			02257nam a2200373Ia 4500
001			CRC00E91158PDF
003			BD-DhSAU
005			20151012144300.0
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007			cr||||
008			110413s2010 fluadf sb 001 0 eng d
020			_a9781420091168 (ebook : PDF)
040			_aBD-DhSAU _cBD-DhSAU
090			_aRM301.42 _b.D68 2010
092			_a615.19072 _bD728
100	1		_aDoucet, Jean-Pierre.
245	1	0	_aThree dimensional QSAR _h[electronic resource] : _bapplications in pharmacology and toxicology / _cJean Pierre Doucet, Annick Panaye.
260			_aBoca Raton : _bCRC Press, _c2010.
300			_axxxiv, 533 p., [8] p. of col. plates : _bill.
490	1		_aQSAR in environmental and health sciences
504			_aIncludes bibliographical references (p. 467-520) and index.
520			_a"Experiencing rapid growth over the last 15 years, quantitative structure-activity relationships (QSAR) continue to evolve quickly with an explosion of new tools and techniques. These techniques now play an increasing role in drug design and chemical risk assessment. New molecular descriptors based on three-dimensional structures incorporate a range of classical approaches, including regression and PLS analysis, as well as new nonlinear approaches, such as neural networks and support vector machines. Three-Dimensional QSAR addresses the scope and limitations of different modeling techniques using case studies from pharmacology, toxicology, and ecotoxicology to demonstrate the utility of each technique"--Provided by publisher.
505	0		_apt. 1. Actual 3D models -- pt. 2. Around the 3D approaches -- pt. 3. Beyond 3D -- pt. 4. Receptor-related models.
530			_aAlso available in print edition.
538			_aMode of access: World Wide Web.
650		0	_aQSAR (Biochemistry)
650		0	_aPharmacology _xResearch _xMethodology.
650		0	_aToxicology _xResearch _xMethodology.
655		7	_aElectronic books. _2lcsh
700	1		_aPanaye, Annick.
776	1		_z9781420091151
830		0	_aQSAR in environmental and health sciences.
856	4	0	_uhttp://marc.crcnetbase.com/isbn/9781420091168 _qapplication/PDF
999			_c11104 _d11103