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003			BD-DhSAU
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008			070829s2008 flua sb 001 0 eng d
020			_a9781420006964 (ebook : PDF)
040			_aBD-DhSAU _cBD-DhSAU
090			_aRS419.5 _b.H537 2008
092			_a615.19 _bH638
245	0	0	_aHigh-throughput lead optimization in drug discovery _h[electronic resource] / _cedited by Tushar Kshirsagar.
260			_aBoca Raton : _bCRC Press, _cc2008.
300			_aix, 243 p. : _bill.
490	0		_aCritical reviews in combinatorial chemistry
504			_aIncludes bibliographical references and index.
505	0		_aApplication of parallel synthesis to the optimization of inhibitors of the ZipA-FtsZ protein-protein interaction / Lee D. Jennings -- Case studies of parallel synthesis in hit identification, hit exploration, hit-to-lead, and lead optimization programs / Alexander Ernst and Daniel Obrecht -- A successful application of parallel synthesis to computer-assisted structural optimization of new leads targeting human immunodeficiency virus-1 reverse transcriptase : the case of acylthiocarbamates and thiocarbamates / Angelo Ranise, Andrea Spallarossa, and Sara Cesarini -- How high-throughput medicinal chemistry can expedite lead discovery, lead optimization, and beyond / Rongshi Li -- Rapid lead identification of inhibitors of adenine nucleotide translocase: a case study of applying combinatorial chemistry techniques in drug discovery / Yazhong Pei, Walter H. Moos, and Soumitra Ghosh -- Parallel synthesis of anticancer, antiinflammatory, and antiviral agents derived from L- and D-amino acids / Robert C. Reid and David P. Fairlie -- Application of solid-phase parallel synthesis in lead optimization studies / Bijoy Kundu -- High-throughput solid-phase synthesis of nucleoside-based libraries in the search for new antibiotics / Dianqing Sun and Richard E. Lee.
530			_aAlso available in print edition. _bCRC Press (http://www.crcpress.com)
538			_aMode of access: World Wide Web.
650		0	_aHigh throughput screening (Drug development)
650		0	_aCombinatorial chemistry.
650		0	_aDrug development.
655		7	_aElectronic books. _2lcsh
700	1		_aKshirsagar, Tushar.
776	1		_z9780849372681
856	4	0	_uhttp://marc.crcnetbase.com/isbn/9781420006964 _qapplication/PDF
999			_c11263 _d11262