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008			070309s2008 flua sb 001 0 eng d
020			_a9781420008272 (ebook : PDF)
040			_aBD-DhSAU _cBD-DhSAU
090			_aRS403 _b.C424 2008
092			_a615.19 _bC517
245	0	0	_aChemistry and molecular aspects of drug design and action _h[electronic resource] / _c[edited by] E.A. Rekka, P.N. Kourounakis.
260			_aBoca Raton : _bCRC Press/Taylor & Francis, _cc2008.
300			_axxii, 356 p. : _bill.
504			_aIncludes bibliographical references and index.
505	0		_aInflammatory mechanisms in Alzheimer's disease and other neurodegenerative disorders / Joseph Rogers ... [et al.] -- Treatment development strategies for Alzheimer's disease / Ernst W�ulfert -- Lipoprotein-associated phospholipase A2 as a new prognostic factor for coronary artery disease / Alexandros D. Tselepis -- New molecular targets for the prevention and treatment of gastrointestinal ulcers and inflammation / Sandor Szabo ... [et al.] -- Stress activates corticotropin releasing : factor signaling pathways : implication in functional bowel disorders / Yvette Tach�e -- Design, synthesis, and pharmacological evaluation of high-affinity and selectivity sigma-1 and sigma-2 receptor ligands / Jacques H. Poupaert -- Synthesis of biologically active taxoids / K.C. Nicolaou and R.K. Guy -- From the molecular pharmacology to the medicinal chemistry of cannabinoids / Didier M. Lambert -- An appraisal of fomocaines : current situation and outlook / Herbert Oelschl�ager and Andreas Seeling -- Ligands for the GABA recognition site at the GABAA receptor : structure-activity studies / Bente Fr�lund ... [et al.] -- Strategies for development of new lead structures for inhibition of acetylcholinesterase / Petra Kapkova ... [et al.] -- Discovery of potent and selective inhibitors of human aldosterone synthase (CYP11B2) : a new target for the treatment of congestive heart failure and myocardial fibrosis--a review / R.W. Hartmann ... [et al.] --
505	0		_aThiocarboxanilides : a new class of nonnucleoside reverse transcriptase inhibitors (NNRTIs) with great potential for the treatment of human immunodeficiency virus type 1 (HIV-1) infections / E. De Clercq, A. Karlsson, and J. Balzarini -- Histamine H3-receptor agonists and antagonists : chemical, pharmacological, and clinical aspects / Holger Stark and Walter Schunack -- Anti-inflammatory actions of flavonoids and structural requirements for new design / Theoharis C. Theoharides -- Molecular mechanisms of H2O2-induced DNA damage : the action of desferrioxamine / M. Tenopoulou, P.-T Doulias, and D. Galaris -- LNA (locked nucleic acid) and functionalized LNA : towards efficient gene targeting / Jesper Wengel -- The effect of diet on drug metabolism / K.J. Netter -- Cytochromes P450 in the metabolism and bioactivation of chemicals / Costas Ioannides -- In vitro methods to measure drug metabolism and drug interactions in drug discovery and development / O. Pelkonen ... [et al.] -- How to probe the sites of action of drug molecules / A. Makriyannis and F. Bitter -- Physicochemical profiling in early drug discovery : new challenges at the age of high-throughput screen and combinatorial chemistry / Bernard Faller -- Drug membrane interaction and its importance for drug efficacy / J.K. Seydel ... [et al.] -- The fight against AIDS : new avenues for inhibiting reverse transcriptase (RT), and old target / Maurizio Botta ... [et al.].
530			_aAlso available in print edition. _bCRC Press (http://www.crcpress.com)
538			_aMode of access: World Wide Web.
650		0	_aPharmaceutical chemistry.
650		0	_aDrugs _xDesign.
655		7	_aElectronic books. _2lcsh
700	1		_aRekka, E. A.
700	1		_aKourounakis, P. N.
776	1		_z9780849390067
856	4	0	_uhttp://marc.crcnetbase.com/isbn/9781420008272 _qapplication/PDF
999			_c11276 _d11275