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008			130702s2012 fluab sb 001 0 eng d
020			_a9780203120187 (ebook : PDF)
040			_aBD-DhSAU _cBD-DhSAU
090			_aTD427.A77 _bM48 2012
092			_a612.3926 _bM587
245	0	4	_aThe metabolism of arsenite _h[electronic resource] / _ceditors: Joanne M. Santini & Seamus A. Ward.
250			_a1st ed.
260			_aBoca Raton, Fla. : _bCRC Press, _c2012.
300			_axxv, 189 p. : _bill. (some col.), maps.
490	1		_aArsenic in the environment, _x1876-6218 ; _vv. 5
504			_aIncludes bibliographical references and index.
505	0		_a1. Arsenic in the environment / D. Kossoff & K.A. Hudson-Edwards -- 2. Giant Mine,Yellowknife, Canada : arsenite waste as the legacy of gold mining and processing / M. Bromstad & H.E. Jamieson -- 3. Genotoxic and carcinogenic risk of arsenic exposure : influence of interindividual genetic variability / R. Marcos & A. Hern�ndez -- 4. Overview of microbial arsenic metabolism and resistance / J.F. Stolz -- 5. Prokaryotic aerobic oxidation of arsenite / T.H. Osborne & J.M. Santini -- 6. Anaerobic oxidation of arsenite by autotrophic bacteria : the view from Mono Lake, California / R.S. Oremland, J.F. Stolz & C.W. Saltikov -- 7. Arsenite oxidase / M.D. Heath, B. Schoepp-Cothenet, T.H. Osborne & J.M. Santini -- 8. Microbial arsenic response and metabolism in the genomics era / P.N. Bertin, L. Geist, D. Halter, S. Koechler, M. Marchal & F. Ars�ne-Ploetze -- 9. Arsenite oxidation : regulation of gene expression / M. Wojnowska & S. Djordjevic -- 10. Evolution of arsenite oxidation / R. van Lis, W. Nitschke, S. Duval & B. Schoepp-Cothenet -- 11. Remediation using arsenite-oxidizing bacteria / F. Delavat, M.-C. Lett & D. Li�vremont -- 12. Development of biosensors for the detection of arsenic in drinking water / C. French, K. de Mora, N. Joshi, A. Elfick, J. Haseloff & J. Ajioka.
520			_a"Up to 200 million people in 70 countries are at risk from drinking water contaminated with arsenic, which is a major cause of chronic debilitating illnesses and fatal cancers. Until recently little was known about the mobility of arsenic, and how redox transformations determined its movement into or out of water supplies. Although human activities contribute to the release of arsenic from minerals, it is now clear that bacteria are responsible for most of the redox transformation of arsenic in the environment. Bacterial oxidation of arsenite (to the less mobile arsenate) has been known since 1918, but it was not until 2000 that a bacterium was shown to gain energy from this process. Since then a wide range of arsenite-oxidizing bacteria have been isolated, including aerobes and anaerobes; heterotrophs and autotrophs; thermophiles, mesophiles and psychrophiles. This book reviews recent advances in the study of such bacteria. After a section on background geology and health issues the main body of the book concerns the cellular machinery of arsenite oxidation. It concludes by examining possible applications. Topics treated are: The geology and cycling of arsenic Arsenic and disease Arsenite oxidation: physiology, enzymes, genes, and gene regulation. Community genomics and functioning, and the evolution of arsenite oxidation Microbial arsenite oxidation in bioremediation Biosensors for arsenic in drinking water and industrial effluents"-- _cProvided by publisher.
520			_a"Arsenite contamination of drinking water is a major cause of chronic illness and mortality in many countries, but until recently little was known of the processes determining its movement and concentration. Bacterial oxidation of arsenite was first described in 1918 and thought to be a means of detoxification. It was not until 2000 that the first autotrophic arsenite-oxidising bacterium was isolated and shown to gain energy from arsenite oxidation. Since then a wide range of such bacteria has been isolated and the literature on the topic has grown rapidly. This book reviews the new understanding of the diversity and abundance of such organisms, their role in arsenic cycling in the environment and their possible relations with arsenic-dependent diseases in humans"-- _cProvided by publisher.
530			_aAlso available in print edition.
538			_aMode of access: World Wide Web.
650		0	_aArsenic _xMetabolism.
650		0	_aArsenic _xEnvironmental aspects.
650		0	_aDrinking water _xArsenic content.
650		0	_aArsenic in the body.
650		0	_aArsenic cycle (Biogeochemistry)
655		7	_aElectronic books. _2lcsh
700	1		_aSantini, Joanne M.
700	1		_aWard, Seamus A.
776	1		_z9780415697194 (hardback) _z0415697190 (hardback)
830		0	_aArsenic in the environment ; _vv. 5.
856	4	0	_uhttp://marc.crcnetbase.com/isbn/9780203120187 _qapplication/PDF
999			_c11350 _d11349