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008 131227t20142014flua ob 001 0 eng d
020 _a9781466508804 (ebook : PDF)
040 _aBD-DhSAU
_beng
_cBD-DhSAU
_erda
090 _aQD477
_b.S54 2014
092 _a546.24
_bS555
100 1 _aShields, George C.
_q(George Charles),
_d1959-
_eauthor.
245 1 0 _aComputational approaches for the prediction of pKa values /
_cGeorge C. Shields, Paul G. Seybold.
264 1 _aBoca Raton :
_bCRC Press,
_c[2014]
264 4 _c�2014
300 _a1 online resource :
_btext file, PDF
336 _atext
_2rdacontent
337 _acomputer
_2rdamedia
338 _aonline resource
_2rdacarrier
490 1 _aQSAR in environmental and health sciences ;
_v4
504 _aIncludes bibliographical references and index.
505 0 _achapter 1. Introduction -- chapter 2. Absolute pKa calculations -- chapter 3. Relative pKa calculations -- chapter 4. Quantitative structure-acidity methods -- chapter 5. Oxyacids and related compounds -- chapter 6. Nitrogen acids -- chapter 7. Additional types of acids -- chapter 8. Acidities in nonaqueous solvents -- chapter 9. Additional factors influencing acidity and basicity -- chapter 10. Conclusions.
520 _a"The book describes how one can calculate the acidities and basicities of chemicals (pKa is the dissociation constant). Many drugs, industrial chemicals, biochemicals and pollutants dissociate to form new species under different conditions. The nature of the species present has a profound effect on how the species act, and it is important to be able to estimate which species will be present under different conditions. No other book summarizes how one can estimate the natures of the species present using modern theoretical methods. This book fills that need"--
_cProvided by publisher.
530 _aAlso available in print format.
650 0 _aAcids
_xBasicity.
650 0 _aDissociation.
650 0 _aChemistry, Physical and theoretical.
655 7 _aElectronic books.
_2lcsh
700 1 _aSeybold, Paul G.,
_eauthor.
776 0 8 _iPrint version:
_z9781466508781 (hardback)
830 0 _aQSAR in environmental and health sciences ;
_v4.
856 4 0 _uhttp://marc.crcnetbase.com/isbn/9781466508804
_qapplication/PDF
999 _c11426
_d11425