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008			110310s2011 fluacd sb 001 0 eng d
020			_a9781439809655 (ebook : PDF)
040			_aBD-DhSAU _cBD-DhSAU
090			_aQP552.M46 _bP765 2011
092			_a572.633 _bP967
245	0	0	_aProtein folding and metal ions _h[electronic resource] : _bmechanisms, biology and disease / _cedited by Cl�audio M. Gomes, Pernilla Wittung-Stafshede.
260			_aBoca Raton : _bCRC Press, _c2011.
300			_axiv, 294 p. : _bill., port.
504			_aIncludes bibliographical references and index.
505	8		_a(Publisher-supplied data) ch. 1. Metal ions, protein folding, and conformational states : an introduction / Cl�audio M. Gomes and Pernilla Wittung-Stafshede -- ch. 2. The folding mechanism of c-type cytochromes / Carlo Travaglini-Allocatelli, Stefano Gianni, and Maurizio Brunori -- ch. 3. The mechanism of cytochrome C folding : early events and kinetic intermediates / Eefei Chen, Robert A. Goldbeck, and David S. Kliger -- ch. 4. Stability and folding of copper-binding proteins / Irina Pozdnyakova and Pernilla Wittung-Stafshede -- ch. 5. Iron-sulfur clusters, protein folds, and ferredoxin stability / S�onia S. Leal and Cl�audio M. Gomes -- ch. 6. Folding and stability of myoglobins and hemoglobins / David S. Culbertson and John S. Olson -- ch. 7. Frataxin : an unusual metal-binding protein in search of a function / Annalisa Pastore -- ch. 8. Mechanism of human copper transporter Wilson's Disease protein / Amanda Barry, Zara Akram, and Svetlana Lutsenko -- ch. 9. A-Synuclein and metals / Aaron Santner and Vladimir N. Uversky -- ch. 10. Zinc and p53 misfolding / James S. Butler and Stewart N. Loh -- ch. 11. The octarepeat domain of the prion protein and its role in metal ion coordination and disease / Glenn L. Millhauser -- ch. 12. Metallopeptides as tools to understand metalloprotein folding and stability / Brian R. Gibney -- ch. 13. The folding landscapes of metalloproteins / Patrick Weinkam and Peter G. Wolynes.
520			_a"Interest in the uses and applications of metallo-chemistry in the life sciences continues to expand. This book provides a broad overview of metals and protein folding. It addresses fundamental aspects of the folding, stability, and design of metal binding proteins and peptides along with biological aspects related to the action of metallochaperones. The text features practical information related to methodologies, particular techniques, and bibliographic references. Readers will gain the molecular basis for protein-metal interactions and a good perspective on the applications of protein coordination chemistry in life sciences and biotechnology"--Provided by publisher.
530			_aAlso available in print edition.
538			_aMode of access: World Wide Web.
650		0	_aMetalloproteins.
650		0	_aProtein folding.
655		7	_aElectronic books. _2lcsh
700	1		_aGomes, Cl�audio M., _d1970-
700	1		_aWittung-Stafshede, Pernilla, _d1968-
776	1		_z9781439809648
856	4	0	_uhttp://marc.crcnetbase.com/isbn/9781439809655 _qapplication/PDF
999			_c11569 _d11568