| 000 | 03030nam a2200325Ia 4500 | ||
|---|---|---|---|
| 001 | CRC0KE10940PDF | ||
| 003 | BD-DhSAU | ||
| 005 | 20151012144304.0 | ||
| 006 | m|||||o||d|||||||| | ||
| 007 | cr|||| | ||
| 008 | 110525s2011 fluad sb 001 0 eng d | ||
| 020 | _a9781439819944 (ebook : PDF) | ||
| 040 |
_aBD-DhSAU _cBD-DhSAU |
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| 090 |
_aQP625.O47 _bH36 2011 |
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| 092 |
_a572.85 _bH236 |
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| 245 | 0 | 0 |
_aHandbook of analysis of oligonucleotides and related products _h[electronic resource] / _cedited by Jose V. Bonilla, G. Susan Srivatsa. |
| 260 |
_aBoca Raton, Fla. : _bCRC Press, _c2011. |
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| 300 |
_axiv, 497 p. : _bill. |
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| 504 | _aIncludes bibliographical references and index. | ||
| 505 | 0 | _ach. 1. Purity analysis and impurities determination by reversed-phase high-performance liquid chromatography / Hagen Cramer, Kevin J. Finn, and Eric Herzberg -- ch. 2. Purity analysis and impurities determination by AEX-HPLC / Jim Thayer, Veeravagu Murugaiah, and Yansheng Wu -- ch. 3. Purity analysis and molecular weight determination by size exclusion HPLC / Ming Fai Chan and Ipsita Roymoulik -- ch. 4. Analysis of oligonucleotides by liquid chromatography and mass spectrometry / Soheil Pourshahian and Sean M. McCarthy -- ch. 5. Sequence determination and confirmation by MS/MS and MALDI-TOF / Zoltan Timar -- ch. 6. Tm analysis of oligonucleotides / Huihe Zhu and G. Susan Srivatsa -- ch. 7. Purity and content analysis of oligonucleotides by capillary gel electrophoresis / Judy Carmody and Bernhard Noll -- ch. 8. Bioanalysis of therapeutic oligonucleotides using hybridization-based immunoassay techniques / Helen Legakis and Sandra Carriero -- | |
| 505 | 8 | _ach. 9. Oligonucleotide assay and potency / Dennis P. Michaud -- ch. 10. Microbial analysis : endotoxin testing / Barbara J. Markley -- ch. 11. Analysis of residual solvents by head space gas chromatography / Sky Countryman and Jose V. Bonilla -- ch. 12. Determination of extinction coefficient / Veeravagu Murugaiah -- ch. 13. Structural determination by NMR / Michele L. DeRider, Doug Brooks, and Gary Burt -- ch. 14. Infrared analysis of oligonucleotides / Jose V. Bonilla -- ch. 15. Stability indicating methods for oligonucleotide products / Veeravagu Murugaiah -- ch. 16. Analysis by hydrophilic interaction chromatography / Renee N. Easter and Patrick A. Limbach -- ch. 17. Determination of base composition / H�useyin Ayg�un -- ch. 18. Analysis of metals in oligonucleotides / Michael P. Murphy -- ch. 19. Regulatory considerations for the development of oligonucleotide therapeutics / G. Susan Srivatsa. | |
| 530 | _aAlso available in print edition. | ||
| 538 | _aMode of access: World Wide Web. | ||
| 650 | 0 |
_aOligonucleotides _xAnalysis. |
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| 655 | 7 |
_aElectronic books. _2lcsh |
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| 700 | 1 | _aBonilla, Jose V. | |
| 700 | 1 | _aSrivatsa, Susan. | |
| 776 | 1 | _z9781439819937 | |
| 856 | 4 | 0 |
_uhttp://marc.crcnetbase.com/isbn/9781439819944 _qapplication/PDF |
| 999 |
_c11580 _d11579 |
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