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008 130702s2009 nyuadf sb 001 0 eng d
020 _a9781420054385 (ebook : PDF)
040 _aBD-DhSAU
_cBD-DhSAU
090 _aRA1224.45
_b.D47 2009
092 _a618.32
_bD489
245 0 0 _aDevelopmental toxicology
_h[electronic resource].
250 _a3rd ed. /
_bedited by Deborah K. Hansen, Barbara D. Abbott.
260 _aNew York :
_bInforma Healthcare,
_cc2009.
300 _ax, 384 p., [8] p. of plates :
_bill. (some col.).
490 1 _aTarget organ toxicology series ;
_vv. 27
504 _aIncludes bibliographical references and index.
505 0 _a1. Role of apoptosis in normal and abnormal development / Philip Mirkes -- 2. Signal transduction pathways as targets for teratogens / Barbara D. Abbott -- 3. Nutrition in developmental toxicology / Deborah K. Hansen -- 4. Epigenetic mechanisms : role of DNA methylation, histone modifications, and imprinting / Robert G. Ellis-Hutchings and John M. Rogers -- 5. Personalized nutrition and medicine in perinatal development / Jim Kaput, James J. Chen, and William Slikker, Jr. -- 6. Targeted gene changes affecting developmental toxicity / Sid Hunter and Phillip Hartig -- 7. Use of mammalian in vitro systems, including embryonic stem cells, in developmental toxicity testing / Terence R.S. Ozolin�s -- 8. Zebrafish : a nonmammalian model of developmental toxicology / Kimberly C. Brannen ... [et al.] -- 9. Physiologically based pharmacokinetic modeling in the risk assessment of developmental toxicants / Mathieu Valcke and Kannan Krishnan -- 10. Integration of whole animal developmental toxicity data into risk assessment / Mark E. Hurtt and Gregg D. Cappon -- 11. Genomic approaches in developmental toxicology / George P. Daston and Jorge M. Naciff -- 12. Comparative bioinformatics and computational toxicology / Thomas B. Knudsen and Robert J. Kavlock -- 13. Investigating drug effects in human pregnancy / Christina D. Chambers.
530 _aAlso available in print edition.
538 _aMode of access: World Wide Web.
650 0 _aDevelopmental toxicology.
650 0 _aFetus
_xEffect of drugs on.
650 0 _aTeratogenic agents.
655 7 _aElectronic books.
_2lcsh
700 1 _aHansen, Deborah Kay,
_d1952-
700 1 _aAbbott, Barbara D.
776 1 _z9781420054378 (hardcover : alk. paper)
_z1420054376 (hardcover : alk. paper)
830 0 _aTarget organ toxicology series ;
_vv. 27.
856 4 0 _uhttp://marc.crcnetbase.com/isbn/9781420054385
_qapplication/PDF
999 _c12036
_d12035