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Adaptive and flexible clinical trials [electronic resource] / Richard Chin.

By: Chin, RichardMaterial type: TextTextPublication details: Boca Raton, Fla. : CRC Press, 2012. Description: xiii, 184 p. : illISBN: 9781439838334 (ebook : PDF)Subject(s): Clinical trialsGenre/Form: Electronic books.Additional physical formats: No titleOnline resources: Click here to access online Also available in print edition.
Contents:
1. Background -- 2. Conventional statistics -- 3. Statistics used in adaptive clinical trials -- 4. Specific requirements for adaptive trials -- 5. Adaptive randomization and allocation -- 6. Sample size reestimation -- 7. Traditional dosing -- 8. Adaptive dosing -- 9. Interim analysis and adaptive termination of study and study arms -- 10. Adaptive changes in study design and decision rules -- 11. Seamless designs and adaptive clinical trial conduct -- 12. Analysis and interpretation of results.
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"A Chapman & Hall book."

Includes bibliographical references and index.

1. Background -- 2. Conventional statistics -- 3. Statistics used in adaptive clinical trials -- 4. Specific requirements for adaptive trials -- 5. Adaptive randomization and allocation -- 6. Sample size reestimation -- 7. Traditional dosing -- 8. Adaptive dosing -- 9. Interim analysis and adaptive termination of study and study arms -- 10. Adaptive changes in study design and decision rules -- 11. Seamless designs and adaptive clinical trial conduct -- 12. Analysis and interpretation of results.

Also available in print edition.

Mode of access: World Wide Web.

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