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Statistical and computational pharmacogenomics [electronic resource] / Rongling Wu, Min Lin.

By: Wu, RonglingContributor(s): Lin, Min, 1971-Material type: TextTextSeries: Interdisciplinary statisticsPublication details: Boca Raton : Chapman & Hall/CRC, 2008. Description: 368 pISBN: 9781584888291 (ebook : PDF)Subject(s): Pharmacogenetics -- Statistical methods | Pharmacogenetics -- Mathmatical modelsGenre/Form: Electronic books.Additional physical formats: No titleOnline resources: Click here to access online Also available in print edition. CRC Press (http://www.crcpress.com)
Contents:
Designs and strategies for genomic mapping and haplotyping -- Genetic haplotyping in natural populations -- Genetic haplotyping in experimental crosses -- A general genetic model for genetic haplotyping -- Basic principle of functional mapping -- Functional mapping of pharmacokinetics and pharmacodynamics -- Haplotyping drug response with a pharmacokinetics-pharmacodynamics link model -- Functional mapping of biological clocks -- Genetic mapping of allometric scaling -- Functional mapping of drug response with allometric scaling -- Joint functional mapping of drug efficacy and toxicity -- Modeling epistatic interactions in drug response -- Mapping genotype-environment interactions in drug response -- Nonparametric functional mapping of drug response -- Semiparametric functional mapping of drug response.
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Includes bibliographical references and indexes.

Designs and strategies for genomic mapping and haplotyping -- Genetic haplotyping in natural populations -- Genetic haplotyping in experimental crosses -- A general genetic model for genetic haplotyping -- Basic principle of functional mapping -- Functional mapping of pharmacokinetics and pharmacodynamics -- Haplotyping drug response with a pharmacokinetics-pharmacodynamics link model -- Functional mapping of biological clocks -- Genetic mapping of allometric scaling -- Functional mapping of drug response with allometric scaling -- Joint functional mapping of drug efficacy and toxicity -- Modeling epistatic interactions in drug response -- Mapping genotype-environment interactions in drug response -- Nonparametric functional mapping of drug response -- Semiparametric functional mapping of drug response.

Also available in print edition. CRC Press (http://www.crcpress.com)

Mode of access: World Wide Web.

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